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Saccharomyces cerevisiae (S288c)

CDC12

CLA10, PSL7, septin CDC12, L000000348, L000000252, YHR107C

Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells

GO Process (4)

GO Function (6)

GO Component (6)

Gene Ontology Biological Process

maintenance of cell polarity [IMP]

mitotic cytokinesis [IMP]

positive regulation of protein kinase activity [IDA]

septin ring assembly [IDA, IMP]

Gene Ontology Molecular Function

GTP binding [IDA]
GTPase activity [IDA]
phosphatidylinositol-4-phosphate binding [IDA]
phosphatidylinositol-5-phosphate binding [IDA]
protein complex scaffold [IMP]
structural molecule activity [IDA]

Gene Ontology Cellular Component

cellular bud neck septin ring [IDA]

cytoplasm [IDA]

mating projection [IDA]

prospore membrane [IDA]

septin complex [IDA, IPI]

septin filament array [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36540

559292

Interactors 819
Interactions 1,124
Network
PTM Sites 5