BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

ATG7

APG11, APG7, CVT2, L000004701, S000029035, L000004786, YHR171W

Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner

GO Process (8)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

C-terminal protein lipidation [IDA, IMP]

CVT pathway [IMP]

autophagy [IMP]

late nucleophagy [IMP]

macroautophagy [IMP]

mitochondrion degradation [IMP]

piecemeal microautophagy of nucleus [IMP]

protein modification by small protein conjugation [IMP]

Gene Ontology Molecular Function

Atg12 activating enzyme activity [IMP]
Atg8 activating enzyme activity [IMP]

Gene Ontology Cellular Component

mitochondrion [IDA]

pre-autophagosomal structure [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36605

559292

Interactors 126
Interactions 194
Network