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Saccharomyces cerevisiae (S288c)

YEN1

YER041W

Holliday junction resolvase; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1; similar to S. cerevisiae endonuclease Rth1p

GO Process (2)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

DNA repair [IGI]

cellular response to DNA damage stimulus [IGI]

Gene Ontology Molecular Function

crossover junction endodeoxyribonuclease activity [IDA, IMP]
single-stranded DNA endodeoxyribonuclease activity [ISS]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36777

559292

Interactors 69
Interactions 129
Network
PTM Sites 5