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Saccharomyces cerevisiae (S288c)

DOT6

PBF2, L000004393, YER088C

Protein involved in rRNA and ribosome biogenesis; activated in stochastic pulses of nuclear localization; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; relative distribution to the nucleus increases upon DNA replication stress

GO Process (6)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

chromatin silencing at rDNA [IGI]

chromatin silencing at telomere [IGI]

filamentous growth [IGI]

regulation of transcription from RNA polymerase II promoter [IGI, IMP]

transfer RNA gene-mediated silencing [IMP]

unidimensional cell growth [IMP]

Gene Ontology Molecular Function

sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

Rpd3L-Expanded complex [IDA]

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36833

559292

Interactors 121
Interactions 141
Network
PTM Sites 47