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Saccharomyces cerevisiae (S288c)

SPT2

EXA1, SIN1, L000002028, YER161C

Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components; relocalizes to the cytosol in response to hypoxia; similar to mammalian HMG1 proteins

GO Process (4)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

RNA polyadenylation [IGI, IMP]

chromatin organization [IMP]

negative regulation of transcription from RNA polymerase II promoter [IMP]

transcription elongation from RNA polymerase II promoter [IGI]

Gene Ontology Molecular Function

DNA binding [IDA]
DNA secondary structure binding [IDA]

Gene Ontology Cellular Component

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36914

559292

Interactors 311
Interactions 464
Network
PTM Sites 2