Caenorhabditis elegans
MSH-2
CELE_H26D21.2, H26D21.2
The msh-2 gene encodes a DNA mismatch repair protein homolog that is orthologous to human MSH2 (OMIM:120435); mutation of the human MSH2 gene leads to hereditary non-polyposis colon cancer (OMIM:120436).
GO Process (13)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- double-strand break repair [IBA]
- intra-S DNA damage checkpoint [IBA]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- maintenance of DNA repeat elements [IMP]
- meiotic gene conversion [IBA]
- meiotic mismatch repair [IBA]
- mismatch repair [IMP]
- negative regulation of reciprocal meiotic recombination [IBA]
- postreplication repair [IBA]
- reproduction [IMP]
- response to UV-B [IBA]
- response to X-ray [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
37413
6239
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- Interactors 7
- Interactions 10
- Network