Caenorhabditis elegans
PGP-2
CELE_C34G6.4, glo-5, C34G6.4
pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family and that is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); during development, pgp-2 activity is required, in parallel with that of the AP-3 adaptor complex, for the proper formation of gut granules, lysosome-related organelles found in the C. elegans intestine; pgp-2 is expressed in the intestine, from the E2 stage of embryonic development through adulthood; PGP-2 localizes to the gut granule membrane.
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
37716
6239
Switch View:
- Interactors 4
- Interactions 4
- Network