Caenorhabditis elegans
PABP-2
CELE_C17E4.5, pab-3, C17E4.5
pabp-2 encodes the C. elegans PABPN1 (polyadenylate-binding protein, nuclear 1) ortholog; by homology, PABP-2 is predicted to function as a poly(A)-binding protein involved in several aspects of pre-mRNA processing; large-scale RNAi screens indicate that pabp-2 activity is essential for embryonic and larval development, as well as normal rates of growth and locomotion; in humans, expansion of a polyalanine repeat in PABPN1 is associated with oculopharyngeal muscular dystrophy (OPMD, OMIM:602279).
GO Process (5)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
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- Interactors 11
- Interactions 11
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