CELE_T23H4.2, T23H4.2

nhr-69 encodes a conserved nuclear receptor that is a member of the NR2 subfamily of nuclear receptors that contains Drosophila and human HNF4 (OMIM:600281, mutations in human HNF4A are associated with Type I MODY (maturity-onset diabetes of the young)); by homology, NHR-69 is predicted to function as a transcription factor that may activate or repress transcription in response to a hormonal signal; nhr-69 is expressed strongly in the gut and hypodermis at all stages and is detected in the uterus during the late L4 and adult stages; nhr-69 expression is also occasionally detected in the rectal epithelia and posterior pharynx.

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