Caenorhabditis elegans
IFY-1
CELE_C27A2.3, C27A2.3
ify-1 encodes a rapidly evolving protein ligand of FZY-1, with only 53% identity between C. elegans and C. briggsae and with no visible homologs in more distant species; IFY-1 binds FZY-1 and SEP-1 in yeast two-hybrid assays; ify-1(RNAi) and sep-1(RNAi) animals arrest as one-cell embryos with disorganized chromosomes, supporting the hypothesis that IFY-1 is a securin; the fzy-1(h1983) mutation blocks FZY-1 binding to IFY-1, but not to MDF-2, another possible FZY-1 ligand; IFY-1 protein accumulates abnormally in developmentally arrested one-cell emb-30 embryos.
GO Process (8)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
39223
6239
Switch View:
- Interactors 5
- Interactions 10
- Network