Caenorhabditis elegans

CTH-2

CELE_ZK1127.10, ZK1127.10
cth-2 encodes a putative cystathionine gamma-lyase; CTH-2 is orthologous to human CTH (OMIM:607657, mutated in cystathioninuria), extremely similar to its paralog CTH-1, and also paralogous to CBL-1; either CTH-2, or CTH-1, or both proteins weakly inhibit DHC-1 in vivo; CTH-2 is expressed in both larval and adult hypodermis, anal depressor muscle, and body wall muscle, as well as in adult vulval muscle and reproductive system; CTH-2 binds SMN-1 in yeast two-hybrid assays.
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  • Interactors 20
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