Caenorhabditis elegans
CCT-2
CELE_T21B10.7, T21B10.7
cct-2 encodes a putative beta subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT2 (OMIM:605139); CCT-2 is expressed in most, if not all, tissues; CCT-2 represses SKN-1-dependent transcription of gst-4; CCT-2 is expressed in touch receptor neurons in a MEC-3-dependent fashion; in mass RNAi assays, CCT-2 is required for normal transgene repression and subcellular localization, embryonic osmotic integrity, embryonic and larval viability, fertility, vulval development, and body color.
GO Process (8)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
- apoptotic process [IMP]
- determination of adult lifespan [IMP]
- embryo development ending in birth or egg hatching [IMP]
- hermaphrodite genitalia development [IMP]
- nematode larval development [IMP]
- positive regulation of multicellular organism growth [IMP]
- receptor-mediated endocytosis [IMP]
- reproduction [IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
39748
6239
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- Interactors 17
- Interactions 18
- Network