Caenorhabditis elegans
TBG-1
CELE_F58A4.8, TUBG, sas-3, F58A4.8
tbg-1 encodes gamma-tubulin; in C. elegans, tbg-1 activity is essential and is required for normal bipolar spindle assembly and function, as well as the fast phase of female pronuclear migration following fertilization; while tbg-1 is required for proper organization and function of kinetochore and interpolar microtubules, it does not appear to be absolutely required for microtubule nucleation and growth; TBG-1 localizes to centrosomes in both interphase and mitotic cells, exhibiting a dynamic behavior during mitosis that differs between anterior and posterior centrosomes.
GO Process (12)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- apoptotic process [IMP]
- cytokinesis [IMP]
- embryo development ending in birth or egg hatching [IMP]
- hatching [IMP]
- hermaphrodite genitalia development [IMP]
- inductive cell migration [IMP]
- microtubule nucleation [IMP]
- mitotic nuclear division [IMP]
- mitotic sister chromatid segregation [IMP]
- mitotic spindle organization [IMP]
- receptor-mediated endocytosis [IMP]
- reproduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
41556
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- Interactors 17
- Interactions 17
- Network