Caenorhabditis elegans

KLO-1

CELE_C50F7.10, C50F7.10
klo-1 encodes a homolog of the human beta-glucosidase-like proteins KL (klotho; OMIM:604824, variant in coronary artery disease), KLB (beta-klotho; OMIM:611135), GBA3 (cytosolic beta-glucosidase; OMIM:606619), LCT (lactase-phlorizin hydrolase; OMIM:603202, variant in adult lactose tolerance), and LCTL (lactase-like protein); KLO-1 has 76% identity (364/478 residues) to its paralog encoded by klo-2; perhaps due to genetic redundancy, klo-1 has no obvious function in mass RNAi assays.
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  • Interactors 5
  • Interactions 6
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