Caenorhabditis elegans

DYF-19

CELE_Y43F8C.4, Y43F8C.4
dyf-19 encodes the C. elegans ortholog of mammalian transition fibre protein FBF1 (Fas (TNFRSF6)-binding factor 1); DYF-19 is required for actively regulating transit of assembled intraflagellar transport (IFT) particles through the ciliary base, and thus for proper ciliogenesis; DYF-19 physically interacts with DYF-11, a component of the IFT-B subcomplex orthologous to mammalian IFT54; DYF-19 localizes to ciliary transition fibers.
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