Caenorhabditis elegans
UNC-97
CELE_F14D12.2, F14D12.2
The unc-97 gene encodes a LIM domain-containing protein of the PINCH family that is highly similar to human LIMS1 (OMIM:602567) and LIMS2; UNC-97 functions as an adaptor protein important for assembly of muscle adherens junctions and the mechanosensory functions of the touch neurons; UNC-97 interacts with PAT-4/integrin-linked kinase and with UNC-98; UNC-97 colocalizes with PAT-3/beta integrin at dense bodies, focal adhesion-like muscle attachment structures.
GO Process (11)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- body morphogenesis [IMP]
- cell-cell junction organization [IMP]
- embryo development ending in birth or egg hatching [IMP]
- lipid storage [IMP]
- locomotion [IMP]
- muscle organ development [IMP]
- nematode larval development [IMP]
- protein catabolic process [IMP]
- receptor-mediated endocytosis [IMP]
- sensory perception of mechanical stimulus [IMP]
- striated muscle contraction involved in embryonic body morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
45760
6239
Switch View:
- Interactors 24
- Interactions 28
- Network