Caenorhabditis elegans
MRP-4
CELE_F21G4.2, F21G4.2
mrp-4 encodes a putative member of subfamily C of the ATP-binding cassette transporters; MRP-4 is required, redundantly with its paralog WHT-2, for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; hermaphrodites subjected to double wht-2(RNAi) mrp-4(RNAi) are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them; in mammalian eicosanoid signalling, subfamily C ABC transporters are required for PUFA and eicosanoid transport.
GO Process (3)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
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46117
6239
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- Interactors 3
- Interactions 3
- Network