Rattus norvegicus
RYR2
RYR-2, RyR
ryanodine receptor 2, cardiac
GO Process (42)
GO Function (16)
GO Component (20)
Gene Ontology Biological Process
- BMP signaling pathway [ISO]
- Purkinje myocyte to ventricular cardiac muscle cell signaling [ISO]
- calcium ion transmembrane transport [IMP, ISO]
- calcium ion transport [ISO, ISS]
- calcium ion transport into cytosol [ISO]
- calcium-mediated signaling [ISO, ISS]
- calcium-mediated signaling using intracellular calcium source [ISO]
- canonical Wnt signaling pathway [ISO]
- cardiac muscle contraction [ISO]
- cardiac muscle hypertrophy [ISO]
- cellular calcium ion homeostasis [ISO, ISS]
- cellular response to caffeine [ISO, ISS]
- cytosolic calcium ion homeostasis [IMP]
- cytosolic calcium ion transport [ISO]
- detection of calcium ion [ISO]
- embryonic heart tube morphogenesis [ISO, ISS]
- establishment of protein localization to endoplasmic reticulum [ISO]
- ion transmembrane transport [IMP]
- left ventricular cardiac muscle tissue morphogenesis [ISO]
- manganese ion transmembrane transport [IMP]
- negative regulation of cytosolic calcium ion concentration [IDA]
- positive regulation of calcium-transporting ATPase activity [ISO]
- positive regulation of heart rate [ISO]
- positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction [ISO]
- positive regulation of sequestering of calcium ion [ISO]
- positive regulation of the force of heart contraction [ISO]
- regulation of cardiac muscle contraction [ISO]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [ISO]
- regulation of heart rate [ISO]
- release of sequestered calcium ion into cytosol [ISO]
- release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [ISO]
- response to caffeine [ISO]
- response to calcium ion [IDA]
- response to drug [IEP]
- response to hypoxia [ISO]
- response to magnesium ion [IDA]
- response to muscle stretch [ISO]
- response to nutrient [IEP]
- response to redox state [ISO]
- sarcoplasmic reticulum calcium ion transport [IMP]
- type B pancreatic cell apoptotic process [ISO]
- ventricular cardiac muscle cell action potential [ISO]
Gene Ontology Molecular Function- calcium channel activity [ISO, ISS]
- calcium-induced calcium release activity [IDA, ISO]
- calcium-release channel activity [ISO]
- calmodulin binding [ISO]
- enzyme binding [ISO]
- identical protein binding [ISO]
- intracellular ligand-gated calcium channel activity [ISO, ISS]
- organic cyclic compound binding [ISO]
- protein binding [IPI]
- protein kinase A catalytic subunit binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein self-association [ISO]
- ryanodine-sensitive calcium-release channel activity [IDA, IMP, ISO]
- scaffold protein binding [IPI]
- suramin binding [ISO]
- calcium channel activity [ISO, ISS]
- calcium-induced calcium release activity [IDA, ISO]
- calcium-release channel activity [ISO]
- calmodulin binding [ISO]
- enzyme binding [ISO]
- identical protein binding [ISO]
- intracellular ligand-gated calcium channel activity [ISO, ISS]
- organic cyclic compound binding [ISO]
- protein binding [IPI]
- protein kinase A catalytic subunit binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein self-association [ISO]
- ryanodine-sensitive calcium-release channel activity [IDA, IMP, ISO]
- scaffold protein binding [IPI]
- suramin binding [ISO]
Gene Ontology Cellular Component
- A band [IDA]
- Z disc [IDA, ISO]
- calcium channel complex [ISO]
- cell [ISO]
- cytoplasm [IDA]
- cytosol [ISO]
- endoplasmic reticulum [IDA]
- extracellular vesicular exosome [ISO]
- extrinsic component of cytoplasmic side of plasma membrane [IDA]
- intracellular [ISO]
- membrane [ISO]
- neuron projection [IDA]
- nuclear envelope [IDA]
- plasma membrane [IDA]
- protein complex [IDA, ISO]
- sarcolemma [IDA]
- sarcomere [ISO]
- sarcoplasmic reticulum [IDA, ISO]
- sarcoplasmic reticulum membrane [IDA, ISO]
- smooth endoplasmic reticulum [ISO]
Download Curated Data for this Protein
604379
10116
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- Interactors 4
- Interactions 5
- Network