Homo sapiens
HHEX
HEX, HMPH, HOX11L-PEN, PRH, PRHX
hematopoietically expressed homeobox
GO Process (17)
GO Function (11)
GO Component (3)
Gene Ontology Biological Process
- B cell differentiation [ISS]
- DNA conformation change [IDA]
- anterior/posterior pattern specification [ISS]
- cell differentiation [IC]
- cell proliferation [IDA]
- mRNA export from nucleus [IDA]
- negative regulation of angiogenesis [ISS]
- negative regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
- negative regulation of transcription by competitive promoter binding [TAS]
- negative regulation of transcription by transcription factor localization [IC]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of vascular endothelial growth factor receptor signaling pathway [ISS]
- poly(A)+ mRNA export from nucleus [IMP]
- positive regulation of Wnt signaling pathway [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein localization to nucleus [IDA]
Gene Ontology Molecular Function- DNA binding, bending [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- TBP-class protein binding [TAS]
- eukaryotic initiation factor 4E binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- repressing transcription factor binding [IDA]
- sequence-specific DNA binding [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, TAS]
- DNA binding, bending [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- TBP-class protein binding [TAS]
- eukaryotic initiation factor 4E binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- repressing transcription factor binding [IDA]
- sequence-specific DNA binding [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, TAS]
Download Curated Data for this Protein
109335
9606
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- Interactors 44
- Interactions 55
- Network
- PTM Sites 3