Homo sapiens
TGFB1
CED, DPD1, LAP, TGFB, TGFbeta
transforming growth factor, beta 1
GO Process (102)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- ATP biosynthetic process [IDA]
- MAPK cascade [IMP]
- SMAD protein complex assembly [IDA]
- SMAD protein import into nucleus [IDA]
- SMAD protein signal transduction [IBA]
- active induction of host immune response by virus [TAS]
- blood coagulation [TAS]
- cell cycle arrest [IDA]
- cell-cell junction organization [IDA]
- cellular response to organic cyclic compound [IDA]
- cellular response to transforming growth factor beta stimulus [IDA]
- chondrocyte differentiation [IDA]
- common-partner SMAD protein phosphorylation [IDA]
- connective tissue replacement involved in inflammatory response wound healing [TAS]
- epidermal growth factor receptor signaling pathway [IDA]
- evasion or tolerance of host defenses by virus [IDA]
- extracellular matrix assembly [IDA]
- extracellular matrix organization [TAS]
- extrinsic apoptotic signaling pathway [IDA]
- hematopoietic progenitor cell differentiation [IDA]
- hyaluronan catabolic process [IDA]
- inflammatory response [IDA]
- lipopolysaccharide-mediated signaling pathway [IDA]
- lymph node development [ISS]
- macrophage derived foam cell differentiation [IC]
- mitotic cell cycle checkpoint [IDA]
- modulation by virus of host morphology or physiology [TAS]
- negative regulation of DNA replication [IMP]
- negative regulation of blood vessel endothelial cell migration [IDA]
- negative regulation of cell cycle [IDA]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of cell-cell adhesion [IDA]
- negative regulation of epithelial cell proliferation [IDA, IMP]
- negative regulation of extracellular matrix disassembly [IC]
- negative regulation of fat cell differentiation [IDA]
- negative regulation of gene expression [IDA]
- negative regulation of hyaluronan biosynthetic process [IDA]
- negative regulation of macrophage cytokine production [IDA]
- negative regulation of mitotic cell cycle [IDA]
- negative regulation of myoblast differentiation [IDA]
- negative regulation of protein phosphorylation [IDA]
- negative regulation of skeletal muscle tissue development [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- ossification involved in bone remodeling [IEP]
- pathway-restricted SMAD protein phosphorylation [IDA]
- phosphate-containing compound metabolic process [IDA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of NAD+ ADP-ribosyltransferase activity [IDA]
- positive regulation of SMAD protein import into nucleus [IDA]
- positive regulation of blood vessel endothelial cell migration [IDA]
- positive regulation of bone mineralization [IEP]
- positive regulation of cell migration [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of cellular protein metabolic process [IDA]
- positive regulation of chemotaxis [IDA]
- positive regulation of collagen biosynthetic process [IDA, IMP]
- positive regulation of epithelial to mesenchymal transition [IDA, NAS]
- positive regulation of extracellular matrix assembly [IC]
- positive regulation of fibroblast migration [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of interleukin-17 production [IDA]
- positive regulation of isotype switching to IgA isotypes [IDA]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of peptidyl-threonine phosphorylation [IDA]
- positive regulation of phosphatidylinositol 3-kinase activity [IDA]
- positive regulation of protein complex assembly [IDA]
- positive regulation of protein dephosphorylation [IDA]
- positive regulation of protein import into nucleus [IDA]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of protein secretion [IDA]
- positive regulation of superoxide anion generation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription regulatory region DNA binding [IDA]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- positive regulation vascular endothelial growth factor production [TAS]
- protein export from nucleus [IDA]
- protein import into nucleus, translocation [IDA]
- protein kinase B signaling [IMP]
- protein phosphorylation [ISS]
- receptor catabolic process [IDA]
- regulation of DNA binding [ISS]
- regulation of apoptotic process [IBA]
- regulation of binding [ISS]
- regulation of blood vessel remodeling [IC]
- regulation of cell migration [TAS]
- regulation of miRNA metabolic process [IDA]
- regulation of protein import into nucleus [ISS]
- regulation of striated muscle tissue development [ISS]
- regulation of transforming growth factor beta receptor signaling pathway [IDA]
- response to cholesterol [IDA]
- response to estradiol [IDA]
- response to progesterone [IDA]
- response to wounding [IEP]
- salivary gland morphogenesis [IEP]
- transforming growth factor beta receptor signaling pathway [IDA, TAS]
- viral life cycle [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
112898
9606
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- Interactors 366
- Interactions 411
- Chemical Interactions 8
- Network
- PTM Sites 8