Mus musculus
PPARG
Nr1c3, PPAR-gamma, PPAR-gamma2, PPARgamma, PPARgamma2
peroxisome proliferator activated receptor gamma
GO Process (55)
GO Function (19)
GO Component (5)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- brown fat cell differentiation [IDA]
- cell fate commitment [IGI]
- cell maturation [ISO]
- cellular response to insulin stimulus [ISO]
- cellular response to lithium ion [IDA]
- cellular response to organic cyclic compound [IDA]
- epithelial cell differentiation [IGI]
- fat cell differentiation [IDA, IGI]
- fatty acid oxidation [ISO]
- glucose homeostasis [ISO]
- inflammatory response [TAS]
- intracellular receptor signaling pathway [TAS]
- lipoprotein transport [ISO]
- long-chain fatty acid transport [IMP]
- low-density lipoprotein particle receptor biosynthetic process [ISO]
- monocyte differentiation [ISO]
- negative regulation of acute inflammatory response [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP, ISO]
- negative regulation of cellular response to insulin stimulus [IMP]
- negative regulation of cholesterol storage [ISO]
- negative regulation of collagen biosynthetic process [ISO]
- negative regulation of cytokine production [IMP]
- negative regulation of interferon-gamma-mediated signaling pathway [ISO]
- negative regulation of macrophage derived foam cell differentiation [ISO]
- negative regulation of pancreatic stellate cell proliferation [ISO]
- negative regulation of peptide hormone secretion [IMP]
- negative regulation of receptor biosynthetic process [ISO]
- negative regulation of sequestering of triglyceride [ISO]
- negative regulation of smooth muscle cell proliferation [ISO]
- negative regulation of telomerase activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- peroxisome proliferator activated receptor signaling pathway [ISO]
- placenta development [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of fat cell differentiation [IDA, IGI, IMP, ISO]
- positive regulation of fatty acid oxidation [ISO]
- positive regulation of oligodendrocyte differentiation [ISO]
- positive regulation of phagocytosis, engulfment [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of blood pressure [ISO]
- regulation of fat cell differentiation [IDA, IGI, ISO]
- regulation of lipid metabolic process [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO, TAS]
- regulation of transcription involved in cell fate commitment [IMP]
- response to lipid [IDA]
- response to low-density lipoprotein particle [ISO]
- response to retinoic acid [IDA, ISO]
- signal transduction [ISO]
- transcription from RNA polymerase II promoter [IDA]
- white fat cell differentiation [IDA]
Gene Ontology Molecular Function- DNA binding [IDA, IPI, ISO]
- RNA polymerase II regulatory region DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- WW domain binding [ISO]
- activating transcription factor binding [ISO]
- arachidonic acid binding [IDA]
- chromatin binding [IDA]
- drug binding [ISO]
- enzyme binding [ISO]
- estrogen receptor binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO, TAS]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA, ISO]
- protein binding [IPI]
- protein phosphatase binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [IDA, ISO]
- DNA binding [IDA, IPI, ISO]
- RNA polymerase II regulatory region DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- WW domain binding [ISO]
- activating transcription factor binding [ISO]
- arachidonic acid binding [IDA]
- chromatin binding [IDA]
- drug binding [ISO]
- enzyme binding [ISO]
- estrogen receptor binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [ISO, TAS]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA, ISO]
- protein binding [IPI]
- protein phosphatase binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [IDA, ISO]
Download Curated Data for this Protein
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- Interactors 85
- Interactions 103
- Network
- PTM Sites 2