BioGRID COVID-19 Coronavirus Curation Project
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Mus musculus

TOP1

AI467334, D130064I21Rik, Top-1, RP23-305K11.1

topoisomerase (DNA) I

GO Process (7)

GO Function (7)

GO Component (10)

Gene Ontology Biological Process

DNA replication [IMP]

DNA topological change [IDA, ISO]

chromatin remodeling [IBA, ISO]

chromosome segregation [IBA]

circadian regulation of gene expression [ISO]

embryonic cleavage [IMP]

rRNA transcription [ISO]

Gene Ontology Molecular Function

DNA binding [ISO]
DNA topoisomerase type I activity [IDA, ISO]
chromatin DNA binding [ISO]
chromatin binding [ISO]
core promoter sequence-specific DNA binding [ISO]
poly(A) RNA binding [ISO]
protein complex binding [ISO]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic mRNA processing body [ISO]

dense fibrillar component [ISO]

fibrillar center [ISO]

nuclear chromosome [ISO]

nucleolus [IBA, ISO]

nucleoplasm [ISO]

nucleus [IDA, ISO]

perikaryon [IDA]

replication fork protection complex [IBA]

CRISPR Database VEGA MGI Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Download Curated Data for this Protein

204275

10090

Interactors 46
Interactions 46
Network
PTM Sites 4