Rattus norvegicus
PSEN1
presenilin 1
GO Process (85)
GO Function (7)
GO Component (35)
Gene Ontology Biological Process
- Cajal-Retzius cell differentiation [ISO]
- L-glutamate transport [ISO]
- Notch receptor processing [IBA, ISO]
- Notch signaling pathway [ISO]
- T cell activation involved in immune response [ISO]
- T cell receptor signaling pathway [ISO]
- activation of MAPKK activity [ISO]
- amyloid precursor protein catabolic process [IBA, ISO]
- autophagic vacuole assembly [ISO]
- autophagy [ISO]
- beta-amyloid formation [ISO]
- beta-amyloid metabolic process [IBA, ISO]
- blood vessel development [ISO]
- brain development [ISO]
- brain morphogenesis [ISO]
- calcium ion transmembrane transport [ISO]
- calcium ion transport [IBA]
- canonical Wnt signaling pathway [IBA]
- cell fate specification [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular protein metabolic process [ISO]
- cellular response to DNA damage stimulus [ISO]
- cerebral cortex cell migration [ISO]
- cerebral cortex development [ISO]
- choline transport [ISO]
- dorsal/ventral neural tube patterning [ISO]
- embryonic limb morphogenesis [ISO]
- endoplasmic reticulum calcium ion homeostasis [ISO]
- epithelial cell proliferation [ISO]
- eye photoreceptor cell development [NAS]
- forebrain development [ISO]
- heart development [ISO]
- heart looping [ISO]
- hematopoietic progenitor cell differentiation [ISO]
- learning or memory [ISO]
- locomotion [ISO]
- membrane protein ectodomain proteolysis [IMP, ISO, ISS]
- memory [ISO]
- mitochondrial transport [ISO]
- myeloid dendritic cell differentiation [ISO]
- myeloid leukocyte differentiation [ISO]
- negative regulation of apoptotic process [IDA, ISO]
- negative regulation of apoptotic signaling pathway [ISO]
- negative regulation of axonogenesis [ISO]
- negative regulation of epidermal growth factor-activated receptor activity [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of protein kinase activity [ISO]
- negative regulation of protein phosphorylation [ISO]
- negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of ubiquitin-protein transferase activity [ISO]
- neurogenesis [ISO]
- neuron apoptotic process [ISO]
- neuron development [ISO]
- neuron differentiation [ISO]
- neuron migration [ISO]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of catalytic activity [ISO, ISS]
- positive regulation of coagulation [ISO]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of receptor recycling [ISO]
- post-embryonic development [ISO]
- protein glycosylation [ISO]
- protein maturation [ISO]
- protein processing [IDA, ISO, ISS]
- protein transport [ISO]
- proteolysis [ISO]
- regulation of epidermal growth factor-activated receptor activity [ISO]
- regulation of phosphorylation [ISO]
- regulation of protein binding [ISO]
- regulation of resting membrane potential [ISO]
- regulation of synaptic plasticity [ISO]
- regulation of synaptic transmission, glutamatergic [ISO]
- response to oxidative stress [ISO]
- segmentation [ISO]
- single organismal cell-cell adhesion [ISO]
- skeletal system morphogenesis [ISO]
- skin morphogenesis [ISO]
- smooth endoplasmic reticulum calcium ion homeostasis [IBA, ISO]
- somitogenesis [ISO]
- synaptic vesicle targeting [ISO]
- thymus development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO, ISS]
- Z disc [IBA]
- apical plasma membrane [IBA]
- axon [IBA, ISO]
- cell [ISO]
- cell cortex [IBA]
- cell surface [IDA]
- centrosome [ISO]
- ciliary rootlet [IBA, ISO]
- cytoplasmic vesicle [ISO]
- dendrite [ISO]
- dendritic shaft [IBA, ISO]
- endoplasmic reticulum [IBA, ISO, ISS]
- gamma-secretase complex [ISO]
- growth cone [IBA, ISO]
- integral component of plasma membrane [IBA, ISO, ISS]
- intracellular [ISO]
- kinetochore [ISO]
- lysosomal membrane [IDA]
- membrane [ISO]
- membrane raft [IDA, ISO]
- membrane-bounded organelle [ISO]
- mitochondrial inner membrane [IDA]
- mitochondrion [IDA, ISO, ISS]
- neuromuscular junction [IDA]
- neuron projection [IDA]
- neuronal cell body [IBA, ISO]
- nuclear membrane [ISO]
- nuclear outer membrane [ISO]
- nucleus [IBA, ISO]
- perinuclear region of cytoplasm [IBA]
- plasma membrane [ISO]
- protein complex [IDA]
- rough endoplasmic reticulum [ISO]
- smooth endoplasmic reticulum [ISO]
Download Curated Data for this Protein
247872
10116
Switch View:
- Interactors 3
- Interactions 4
- Network