Rattus norvegicus
TLR4
toll-like receptor 4
GO Process (80)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- B cell proliferation involved in immune response [ISO]
- I-kappaB phosphorylation [ISO]
- activation of MAPK activity [ISO]
- activation of innate immune response [ISO]
- cellular response to lipopolysaccharide [IEP, ISO]
- cellular response to lipoteichoic acid [ISO]
- cellular response to mechanical stimulus [IEP, ISO]
- cellular response to retinoic acid [IEP]
- defense response to Gram-negative bacterium [ISO]
- detection of lipopolysaccharide [ISO, ISS]
- immunoglobulin mediated immune response [IEP]
- inflammatory response [IEP]
- innate immune response [TAS]
- innate immune response-activating signal transduction [IMP]
- interferon-gamma production [ISO]
- intestinal epithelial structure maintenance [ISO]
- leukotriene metabolic process [IDA]
- lipopolysaccharide-mediated signaling pathway [ISO]
- macrophage activation [ISO]
- microglial cell activation [IDA]
- negative regulation of ERK1 and ERK2 cascade [ISO]
- negative regulation of interferon-gamma production [ISO]
- negative regulation of interleukin-17 production [ISO]
- negative regulation of interleukin-23 production [ISO]
- negative regulation of interleukin-6 production [ISO]
- negative regulation of tumor necrosis factor production [ISO]
- nitric oxide production involved in inflammatory response [ISO]
- positive regulation of B cell proliferation [ISO]
- positive regulation of DNA binding [IMP]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of MHC class II biosynthetic process [ISO]
- positive regulation of NF-kappaB import into nucleus [ISO]
- positive regulation of NF-kappaB transcription factor activity [IMP, ISO]
- positive regulation of apoptotic process [IMP]
- positive regulation of chemokine production [ISO]
- positive regulation of inflammatory response [IMP]
- positive regulation of interferon-alpha production [ISO]
- positive regulation of interferon-beta biosynthetic process [ISO]
- positive regulation of interferon-beta production [ISO]
- positive regulation of interferon-gamma production [ISO]
- positive regulation of interleukin-1 production [ISO]
- positive regulation of interleukin-10 production [ISO]
- positive regulation of interleukin-12 biosynthetic process [ISO]
- positive regulation of interleukin-12 production [ISO]
- positive regulation of interleukin-6 production [ISO]
- positive regulation of interleukin-8 biosynthetic process [ISO]
- positive regulation of interleukin-8 production [ISO]
- positive regulation of lymphocyte proliferation [ISO]
- positive regulation of macrophage cytokine production [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of nitric-oxide synthase biosynthetic process [ISO]
- positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [ISO]
- positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of platelet activation [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [IMP]
- positive regulation of stress-activated MAPK cascade [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of tumor necrosis factor biosynthetic process [ISO]
- positive regulation of tumor necrosis factor production [ISO]
- regulation of inflammatory response [ISO]
- regulation of sensory perception of pain [IMP]
- response to activity [IEP]
- response to bacterium [ISO]
- response to ethanol [IMP]
- response to fatty acid [IDA]
- response to glucocorticoid [IEP]
- response to gold nanoparticle [IEP]
- response to hypoxia [IEP]
- response to insulin [IEP]
- response to lipopolysaccharide [IDA, IEP, ISO]
- response to morphine [IEP]
- response to oxidative stress [IMP]
- response to progesterone [IEP]
- response to retinoic acid [IEP]
- response to toxic substance [IEP]
- skeletal muscle contraction [IEP]
- toll-like receptor signaling pathway [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
247933
10116
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