Rattus norvegicus
NEDD4L
Nedd4-2
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
GO Process (26)
GO Function (8)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of potassium ion transmembrane transport [ISO]
- negative regulation of potassium ion transmembrane transporter activity [IMP, ISO]
- negative regulation of protein localization to cell surface [ISO]
- negative regulation of sodium ion transmembrane transport [ISO]
- negative regulation of sodium ion transmembrane transporter activity [ISO]
- negative regulation of sodium ion transport [ISO]
- negative regulation of systemic arterial blood pressure [ISO]
- positive regulation of cation channel activity [ISO]
- positive regulation of caveolin-mediated endocytosis [IMP]
- positive regulation of protein catabolic process [IMP]
- positive regulation of sodium ion transport [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- protein K48-linked ubiquitination [ISO]
- protein monoubiquitination [IMP]
- protein ubiquitination [ISO]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA, ISO]
- regulation of ion transmembrane transport [ISO]
- regulation of membrane depolarization [ISO]
- regulation of membrane potential [ISO]
- regulation of membrane repolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
- regulation of tight junction assembly [ISO]
- response to metal ion [ISO]
- response to salt stress [ISO]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [ISO]
- ventricular cardiac muscle cell action potential [IMP]
Gene Ontology Molecular Function- ion channel binding [ISO]
- potassium channel inhibitor activity [IMP, ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- sodium channel inhibitor activity [ISO]
- sodium channel regulator activity [ISO]
- ubiquitin protein ligase activity [ISO]
- ubiquitin-protein transferase activity [IBA, IDA]
- ion channel binding [ISO]
- potassium channel inhibitor activity [IMP, ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- sodium channel inhibitor activity [ISO]
- sodium channel regulator activity [ISO]
- ubiquitin protein ligase activity [ISO]
- ubiquitin-protein transferase activity [IBA, IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
253555
10116
Switch View:
- Interactors 4
- Interactions 6
- Network
- PTM Sites 1