Rattus norvegicus
MAP3K11
Mlk-3, Mlk3, RHOE
mitogen-activated protein kinase kinase kinase 11
GO Process (13)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- JNK cascade [IDA]
- activation of JNKK activity [IDA]
- activation of JUN kinase activity [ISO]
- activation of MAPK activity [ISO]
- cell death [IMP]
- cell proliferation [ISO]
- microtubule-based process [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of JUN kinase activity [ISO]
- positive regulation of apoptotic process [IMP]
- positive regulation of neuron apoptotic process [IMP]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [IDA, ISO]
Gene Ontology Molecular Function- ATP binding [IDA]
- JUN kinase kinase kinase activity [IDA]
- MAP kinase kinase kinase activity [IDA]
- Rac GTPase binding [IPI]
- identical protein binding [ISO]
- mitogen-activated protein kinase kinase binding [IPI]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein serine/threonine kinase activity [IDA, ISO]
- ATP binding [IDA]
- JUN kinase kinase kinase activity [IDA]
- MAP kinase kinase kinase activity [IDA]
- Rac GTPase binding [IPI]
- identical protein binding [ISO]
- mitogen-activated protein kinase kinase binding [IPI]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein serine/threonine kinase activity [IDA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
259295
10116
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- Interactors 3
- Interactions 5
- Network