Rattus norvegicus
KDM1A
Aof2, Kdm1, RGD1562975
lysine (K)-specific demethylase 1A
GO Process (35)
GO Function (18)
GO Component (4)
Gene Ontology Biological Process
- alternative mRNA splicing, via spliceosome [IEP]
- cell proliferation [ISO]
- cellular response to cAMP [IEP]
- cerebral cortex development [IEP]
- granulocyte differentiation [ISO]
- guanine metabolic process [IMP]
- histone H3-K4 demethylation [IEP, IMP, ISO]
- histone H3-K9 demethylation [ISO]
- in utero embryonic development [ISO]
- muscle cell development [ISO]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [ISO]
- negative regulation of histone H3-K4 methylation [ISO]
- negative regulation of histone H3-K9 methylation [ISO]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- negative regulation of protein binding [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- neuron maturation [IEP]
- pituitary gland development [ISO]
- positive regulation of cell size [IMP]
- positive regulation of chromatin binding [IMP]
- positive regulation of erythrocyte differentiation [ISO]
- positive regulation of hormone biosynthetic process [ISO]
- positive regulation of megakaryocyte differentiation [ISO]
- positive regulation of neural precursor cell proliferation [ISO]
- positive regulation of neuron projection development [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of stem cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- protein demethylation [ISO]
- regulation of primitive erythrocyte differentiation [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- response to fungicide [IEP]
- response to organic cyclic compound [IEP]
Gene Ontology Molecular Function- MRF binding [ISO]
- RNA polymerase II transcription factor binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [IDA, ISO]
- demethylase activity [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- histone demethylase activity [ISO]
- histone demethylase activity (H3-K4 specific) [ISO]
- histone demethylase activity (H3-K9 specific) [ISO]
- histone demethylase activity (H3-dimethyl-K4 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- oxidoreductase activity [ISO]
- p53 binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- MRF binding [ISO]
- RNA polymerase II transcription factor binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [IDA, ISO]
- demethylase activity [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- histone demethylase activity [ISO]
- histone demethylase activity (H3-K4 specific) [ISO]
- histone demethylase activity (H3-K9 specific) [ISO]
- histone demethylase activity (H3-dimethyl-K4 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- oxidoreductase activity [ISO]
- p53 binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
271877
10116
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- Interactors 2
- Interactions 3
- Network