Saccharomyces cerevisiae (S288c)

HSP78

chaperone ATPase HSP78, L000000821, YDR258C

Oligomeric mitochondrial matrix chaperone; cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates

GO Process (5)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

cellular response to heat [IGI, IMP]

mitochondrial genome maintenance [IGI]

protein refolding [IDA, IMP]

protein stabilization [IGI, IMP]

protein unfolding [IMP]

Gene Ontology Molecular Function

ATPase activity [IDA, IMP]
misfolded protein binding [IDA]

Gene Ontology Cellular Component

mitochondrial matrix [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32308

559292

Interactors 649
Interactions 749
Network
PTM Sites 4

Result Summary

HSP78

Gene Ontology Biological Process

Gene Ontology Molecular Function

ATPase activity [IDA, IMP]misfolded protein binding [IDA]

Gene Ontology Cellular Component

ATPase activity [IDA, IMP]
misfolded protein binding [IDA]