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Saccharomyces cerevisiae (S288c)

HYP2

TIF51A, translation elongation factor eIF-5A, eIF-5A, eIF5A, L000000847, L000002307, YEL034W

Translation elongation factor eIF-5A; required for translation of proteins containing polyproline stretches, including Bni1p, and this leads to a requirement for mating projection formation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication

GO Process (5)

GO Function (4)

GO Component (3)

Gene Ontology Biological Process

positive regulation of cytoplasmic translational elongation through polyproline stretches [IMP]

positive regulation of translational elongation [IDA, IGI, IMP]

positive regulation of translational initiation [IDA]

positive regulation of translational termination [IDA]

translational frameshifting [IMP]

Gene Ontology Molecular Function

RNA binding [IDA]
ribosome binding [IPI]
translation elongation factor activity [IDA, IMP]
translation initiation factor activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytosolic ribosome [IPI]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36695

559292

Interactors 1,086
Interactions 1,236
Network
PTM Sites 14