Saccharomyces cerevisiae (S288c)

BRR2

PRP44, RSS1, SLT22, SNU246, L000003100, L000003283, YER172C

RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD

GO Process (1)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [IMP]

Gene Ontology Molecular Function

ATP-dependent RNA helicase activity [IDA, IMP]

Gene Ontology Cellular Component

U4/U6 x U5 tri-snRNP complex [IDA]

U5 snRNP [IDA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36925

559292

Interactors 584
Interactions 918
Network
PTM Sites 6

Result Summary

BRR2

Gene Ontology Biological Process

Gene Ontology Molecular Function

ATP-dependent RNA helicase activity [IDA, IMP]

Gene Ontology Cellular Component