Caenorhabditis elegans
DHC-1
CELE_T21E12.4, spd-4, let-354, T21E12.4
dhc-1 encodes a cytoplasmic dynein heavy chain homolog required in one-cell embryos for pronuclear migration, centrosome separation, centrosome proximity to the male pronucleus, and mitotic spindle orientation, suggesting that DHC-1 helps position the microtubule organizing center; DHC-1 genetically interacts with SPD-5, a coiled-coil centrosomal protein.
GO Process (14)
GO Function (0)
GO Component (5)
Gene Ontology Biological Process
- centrosomal and pronuclear rotation [IMP]
- cytokinesis [IMP]
- embryo development ending in birth or egg hatching [IMP]
- establishment of meiotic spindle orientation [IGI, IMP]
- meiotic nuclear division [IMP]
- mitotic spindle organization [IMP]
- nematode larval development [IMP]
- oocyte development [IMP]
- pronuclear migration [IMP]
- regulation of cell proliferation [IMP]
- regulation of meiosis [IMP]
- reproduction [IMP]
- synaptic transmission, GABAergic [IGI, IMP]
- synaptic vesicle transport [IMP]
Gene Ontology Cellular Component
Download Curated Data for this Protein
37511
6239
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- Interactors 79
- Interactions 102
- Network