CELE_K02B12.1, K02B12.1

ceh-6 encodes a POU family homeodomain protein, homologous to human POU3F4 (OMIM:304400, mutated in conductive deafness 3); ceh-6 is required for embryonic viability, locomotion, and molting, and for regulation of ectodermal and excretory function; ceh-6 activity is also required for transdifferentiation of the Y rectal cell to the PDA neuron during larval development; CEH-6 is expressed dynamically during development and expression includes neurons, the excretory cell, and ectodermal cells; CEH-6 localizes to both the nucleus and the cytoplasm.

38073

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