Caenorhabditis elegans
DPL-1
CELE_T23G7.1, mex-4, T23G7.1
dpl-1 encodes the C. elegans ortholog of mammalian DP, the E2F-heterodimerization partner; dpl-1 is a class B synMuv gene whose activity is required for oogenesis as well as embryonic asymmetry and vulval development; in addition, dpl-1 acts with a subset of class B synMuv genes and the MCD-1 zinc-finger protein to promote the killing process during programmed cell death; DPL-1 is a nuclear protein that is widely expressed throughout development in both somatic and germ cell lineages.
GO Process (8)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- embryo development ending in birth or egg hatching [IMP]
- hermaphrodite genitalia development [IMP]
- locomotion [IMP]
- negative regulation of Ras protein signal transduction [IMP]
- negative regulation of vulval development [IMP]
- programmed cell death [IGI, IMP]
- regulation of cell fate specification [IMP]
- reproduction [IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
39783
6239
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- Interactors 19
- Interactions 23
- Network