Caenorhabditis elegans
APC-11
CELE_F35G12.9, F35G12.9
apc-11 encodes an E3 ubiquitin ligase that is orthologous to subunit 11 of the anaphase promoting complex (APC); apc-11 is required for embryonic development past the one-cell stage; APC-11 functions together with the LET-70/UBC-2 E2-conjugating enzyme: purified APC-11 and LET-70 exhibit ubiquitination activity in vitro.
GO Process (8)
GO Function (2)
GO Component (0)
Gene Ontology Biological Process
- embryo development [IMP]
- embryo development ending in birth or egg hatching [IMP]
- meiotic chromosome segregation [IMP]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [IMP]
- negative regulation of vulval development [IMP]
- oogenesis [IMP]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IDA]
- reproduction [IMP]
Gene Ontology Molecular Function
Download Curated Data for this Protein
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- Interactors 30
- Interactions 34
- Network