Caenorhabditis elegans
ANI-1
CELE_Y49E10.19, Y49E10.19
ani-1 encodes one of three C. elegans anillins; ANI-1 activity is required in the early embryo for cortical contractile events, including polar body extrusion, membrane ruffling, and pseudocleavage; at later stages of development, ANI-1 also plays a role in cuticle formation, coordinated locomotion, vulval development, and male tail formation; in regulating cortical events, ANI-1 appears to function by positively regulating septin (UNC-59 and UNC-61) localization to the contractile ring as well as formation of septin- and NMY-2-containing cortical patches; in telophase embryos, ANI-1 localizes to the cell cortex and cleavage furrow.
GO Process (12)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- collagen and cuticulin-based cuticle development [IMP]
- cortical cytoskeleton organization [IMP]
- embryo development ending in birth or egg hatching [IMP]
- first cell cycle pseudocleavage [IMP]
- hermaphrodite genitalia development [IMP]
- locomotion [IMP]
- nematode larval development [IMP]
- nematode male tail tip morphogenesis [IMP]
- polar body extrusion after meiotic divisions [IMP]
- protein localization [IMP]
- receptor-mediated endocytosis [IMP]
- septin ring organization [IMP]
Gene Ontology Cellular Component
Download Curated Data for this Protein
41851
6239
Switch View:
- Interactors 31
- Interactions 31
- Network