gnrr-8, CELE_Y105C5A.23, Y105C5A.23

daf-38 encodes a G-protein coupled receptor (GPCR) with homology to human gonadotropin-releasing hormone receptor; daf-38 participates in perception of ascr#2 as well as other ascarosides, which are the major small-molecule components of the dauer pheromone and control developmental diapause (dauer), olfactory learning, social behavior and lifespan; daf-38 forms a heterodimer with daf-37 (a GPCR that belongs to the serpentine receptor class w (Srw) family of chemoreceptors) that also participates in perception of the ascaroside, ascr#2), most likely to form a functional receptor complex; daf-38 and daf-37 are expressed in chemosensory neurons.

43521

6239