CELE_C24A8.4, tag-306, C24A8.4

cst-2 encodes a protein kinase that is the C. elegans ortholog of the MST (mammalian Ste20-like) kinases and Drosophila Hippo; CST-2 appears to play a role in the responses to oxidative stress and determination of adult lifespan; in regulating stress response and lifespan, CST-2 functions upstream of the DAF-16/FOXO transcription factor; CST-2 physically interacts with RSF-1, the C. elegans homolog of the Ras-association domain family protein 1.

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