Caenorhabditis elegans
SEK-1
CELE_R03G5.2, esp-2, R03G5.2
SEK-1 encodes a MAPKK (Mitogen-Activated Protein Kinase Kinase); SEK-1 functions in the p38 MAPK cascade that regulates innate immunity; SEK-1 has MAPKK activity; SEK-1 can activate both JNK-1 and PMK-1 in the yeast Hog pathway.
GO Process (14)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
- activation of MAPK activity [IMP]
- activation of MAPK activity involved in innate immune response [IMP]
- defense response [IMP]
- defense response to Gram-negative bacterium [IMP]
- defense response to Gram-positive bacterium [IMP]
- innate immune response [IMP]
- nematode larval development [IMP]
- p38MAPK cascade [IMP]
- positive regulation of oviposition [IMP]
- positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium [IMP]
- protein phosphorylation [IMP]
- response to reactive oxygen species [IMP]
- response to superoxide [IMP]
- stress-activated MAPK cascade [IMP]
Download Curated Data for this Protein
45967
6239
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- Interactors 12
- Interactions 12
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