BAIT
CTBP2
RP11-59C5.2
C-terminal binding protein 2
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of cell proliferation [TAS]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of retinoic acid receptor signaling pathway [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- viral genome replication [TAS]
- white fat cell differentiation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BCAS3
GAOB1, MAAB
breast carcinoma amplified sequence 3
GO Process (17)
GO Function (8)
GO Component (6)
Gene Ontology Biological Process
- Golgi organization [ISS]
- activation of Cdc42 GTPase activity [ISS]
- cellular response to estrogen stimulus [IDA]
- microtubule organizing center organization [ISS]
- negative regulation of Rho GTPase activity [ISS]
- negative regulation of focal adhesion assembly [ISS]
- positive regulation of Cdc42 GTPase activity [ISS]
- positive regulation of actin cytoskeleton reorganization [ISS]
- positive regulation of catalytic activity [IDA]
- positive regulation of endothelial cell migration [ISS]
- positive regulation of filopodium assembly [ISS]
- positive regulation of intracellular protein transport [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of establishment of cell polarity [ISS]
- response to starvation [IBA]
- tube formation [ISS]
- vesicle-mediated transport [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID