BAIT
CHMP2A
BC-2, BC2, CHMP2, VPS2, VPS2A
charged multivesicular body protein 2A
GO Process (9)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- endosomal transport [TAS]
- establishment of protein localization [IMP]
- membrane organization [TAS]
- positive regulation of exosomal secretion [IMP]
- positive regulation of viral release from host cell [IMP]
- regulation of viral process [IMP]
- viral budding via host ESCRT complex [IGI]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
DOCK8
HEL-205, MRD2, ZIR8, RP11-165F24.7
dedicator of cytokinesis 8
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A proteome-scale map of the human interactome network.
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently ... [more]
Cell Nov. 20, 2014; 159(5);1212-26 [Pubmed: 25416956]
Throughput
- High Throughput
Curated By
- BioGRID