BAIT

HAB1

F28P22.4, F28P22_4, homology to ABI1, AT1G72770
protein phosphatase 2C 16
GO Process (0)
GO Function (2)
GO Component (0)
Arabidopsis thaliana (Columbia)
PREY

SNRK2.2

PROTEIN KINASE, SNF1-RELATED PROTEIN KINASE 2-2, SNF1-related protein kinase 2.2, SNRK2-2, SPK-2-2, SRK2D, AT3G50500
serine/threonine-protein kinase SRK2D
Arabidopsis thaliana (Columbia)

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Catalytic mechanism and kinase interactions of ABA-signaling PP2C phosphatases.

Zhou XE, Soon FF, Ng LM, Kovach A, Suino-Powell KM, Li J, Yong EL, Zhu JK, Xu HE, Melcher K

Abscisic acid (ABA) is an essential hormone that controls plant growth, development and responses to abiotic stresses. ABA signaling is mediated by type 2C protein phosphatases (PP2Cs), including HAB1 and ABI2, which inhibit stress-activated SnRK2 kinases and whose activity is regulated by ABA and ABA receptors. Based on biochemical data and our previously determined crystal structures of ABI2 and the ... [more]

Plant Signal Behav May. 01, 2012; 7(5);581-8 [Pubmed: 22516825]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
HAB1 SNRK2.2
Reconstituted Complex
Reconstituted Complex

An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.

Low-BioGRID
-

Curated By

  • BioGRID