BAIT

SOS2

ATSOS2, CBL-INTERACTING PROTEIN KINASE 24, CIPK24, K21B8.3, K21B8_3, SALT OVERLY SENSITIVE 2, SNF1-RELATED PROTEIN KINASE 3.11, SNRK3.11, AT5G35410
CBL-interacting serine/threonine-protein kinase 24
GO Process (1)
GO Function (4)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

SOS1

ARABIDOPSIS NA+/H+ ANTIPORTER 7, ARABIDOPSIS SALT OVERLY SENSITIVE 1, ATNHX7, ATSOS1, F14H20.5, F14H20_5, SALT OVERLY SENSITIVE 1, AT2G01980
sodium/hydrogen exchanger 7
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Activation of the plasma membrane Na/H antiporter Salt-Overly-Sensitive 1 (SOS1) by phosphorylation of an auto-inhibitory C-terminal domain.

Quintero FJ, Martinez-Atienza J, Villalta I, Jiang X, Kim WY, Ali Z, Fujii H, Mendoza I, Yun DJ, Zhu JK, Pardo JM

The plasma membrane sodium/proton exchanger Salt-Overly-Sensitive 1 (SOS1) is a critical salt tolerance determinant in plants. The SOS2-SOS3 calcium-dependent protein kinase complex up-regulates SOS1 activity, but the mechanistic details of this crucial event remain unresolved. Here we show that SOS1 is maintained in a resting state by a C-terminal auto-inhibitory domain that is the target of SOS2-SOS3. The auto-inhibitory domain ... [more]

Proc. Natl. Acad. Sci. U.S.A. Feb. 08, 2011; 108(6);2611-6 [Pubmed: 21262798]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SOS2 SOS1
Biochemical Activity
Biochemical Activity

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Low-BioGRID
1106441

Curated By

  • BioGRID