BAIT

CAO

CHAOS, CHLOROPLAST SIGNAL RECOGNITION PARTICLE 43, CPSRP43, T30B22.25, AT2G47450
chloroplast signal recognition particle component CAO
Arabidopsis thaliana (Columbia)
PREY

CAB2

AB165, F1N18.4, F1N18_4, LHCB1.1, LIGHT HARVESTING CHLOROPHYLL A/B-BINDING PROTEIN 1.1, chlorophyll A/B-binding protein 2, AT1G29920
chlorophyll A/B-binding protein 2
GO Process (5)
GO Function (1)
GO Component (5)
Arabidopsis thaliana (Columbia)

Reconstituted Complex

An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.

Publication

Mechanism of an ATP-independent protein disaggregase: II. distinct molecular interactions drive multiple steps during aggregate disassembly.

Jaru-Ampornpan P, Liang FC, Nisthal A, Nguyen TX, Wang P, Shen K, Mayo SL, Shan SO

The ability of molecular chaperones to overcome the misfolding and aggregation of proteins is essential for the maintenance of proper protein homeostasis in all cells. Thus far, the best studied disaggregase systems are the Clp/Hsp100 family of "ATPases associated with various cellular activities" (AAA(+)) ATPases, which use mechanical forces powered by ATP hydrolysis to remodel protein aggregates. An alternative system ... [more]

J. Biol. Chem. May. 10, 2013; 288(19);13431-45 [Pubmed: 23519468]

Throughput

  • Low Throughput

Curated By

  • BioGRID