BAIT

HYL1

DRB1, DSRNA-BINDING PROTEIN 1, F21M12.9, F21M12_9, HYPONASTIC LEAVES 1, AT1G09700
double-stranded RNA-binding protein 1
Arabidopsis thaliana (Columbia)
PREY

RD2

F2G1.11, F2G1_11, AT2G21620
dessication responsive protein
GO Process (1)
GO Function (0)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Homodimerization of HYL1 ensures the correct selection of cleavage sites in primary miRNA.

Yang X, Ren W, Zhao Q, Zhang P, Wu F, He Y

MicroRNA (miRNA) plays an important role in the control of gene expression. HYPONASTIC LEAVES1 (HYL1) is a double-stranded RNA-binding protein that forms a complex with DICER-LIKE1 (DCL1) and SERRATE (SE) to process primary miRNA (pri-miRNA) into mature miRNA. Although HYL1 has been shown to partner with DCL1 to enhance miRNA accuracy, the mechanism by which HYL1 selects the DCL1-targeted cleavage ... [more]

Nucleic Acids Res. Oct. 29, 2014; 42(19);12224-36 [Pubmed: 25294831]

Throughput

  • Low Throughput

Curated By

  • BioGRID