BAIT

CK1

CKL1, casein kinase 1, AT4G26100
casein kinase 1
GO Process (0)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

ACS5

1-AMINO-1-CYCLOPROPANECARBOXYLATE SYNTHASE, ACC synthase 5, ATACS5, CIN5, CYTOKININ-INSENSITIVE 5, ETHYLENE OVERPRODUCER 2, ETO2, MPA24.15, MPA24_15, AT5G65800
1-aminocyclopropane-1-carboxylate synthase 5
GO Process (4)
GO Function (2)
GO Component (1)
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Casein kinase 1 regulates ethylene synthesis by phosphorylating and promoting the turnover of ACS5.

Tan ST, Xue HW

The casein kinase 1 (CK1) family participates in various cellular processes in eukaryotes, but CK1 function in higher plants remains largely unknown. Here, we characterize the function of Arabidopsis CK1 in the regulation of ethylene biosynthesis. Etiolated seedlings of a CK1.8-deficient mutant, ck1.8-1, showed characteristic ethylene-specific constitutive responses due to overaccumulation of ethylene. Biochemical and physiological studies showed that CK1.8 ... [more]

Cell Rep Dec. 11, 2014; 9(5);1692-702 [Pubmed: 25464840]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CK1 ACS5
Biochemical Activity
Biochemical Activity

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Low-BioGRID
1173106

Curated By

  • BioGRID