BAIT
ORF9B
9b, ns9b, SARS-CoV sars9b, ORF9b, SARS-CoV ORF9b, ORF9B_CVHSA, PRO_0000106137, SARS-CoV-9b
Protein 9b; Accessory protein 9b; ORF-9b
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus
PREY
RPS20
S20
ribosomal protein S20
GO Process (14)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- cytoplasmic translation [IBA]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to (Coronavirus) CoV epidemics. Neither vaccines nor therapeutics are available against human and animal CoVs. Knowledge of host cell proteins that take part in pivotal virus-host interactions could define ... [more]
PLoS Pathog. Oct. 01, 2011; 7(10);e1002331 [Pubmed: 22046132]
Throughput
- High Throughput
Additional Notes
- validated candidates from HTYTH screen
Curated By
- BioGRID