EFNA1
Gene Ontology Biological Process
- angiogenesis [IBA]
- aortic valve morphogenesis [ISS]
- axon guidance [IBA]
- cell migration [IDA]
- cell-cell signaling [TAS]
- endocardial cushion to mesenchymal transition involved in heart valve formation [ISS]
- ephrin receptor signaling pathway [IDA]
- mitral valve morphogenesis [ISS]
- negative regulation of dendritic spine morphogenesis [ISS]
- negative regulation of epithelial to mesenchymal transition [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- regulation of cell adhesion mediated by integrin [IDA]
- regulation of peptidyl-tyrosine phosphorylation [ISS]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
EPHA4
Gene Ontology Biological Process
- corticospinal tract morphogenesis [ISS]
- fasciculation of motor neuron axon [ISS]
- fasciculation of sensory neuron axon [ISS]
- motor neuron axon guidance [ISS]
- negative regulation of axon regeneration [ISS]
- peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of Rho guanyl-nucleotide exchange factor activity [IDA]
- protein autophosphorylation [IDA]
- regulation of Rac GTPase activity [ISS]
- regulation of Rap GTPase activity [ISS]
- regulation of astrocyte differentiation [ISS]
- regulation of axonogenesis [ISS]
- regulation of dendritic spine morphogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum.
The striatum integrates limbic and neocortical inputs to regulate sensorimotor and psychomotor behaviors. This function is dependent on the segregation of striatal projection neurons into anatomical and functional components, such as the striosome and matrix compartments. In the present study the association of ephrin-A cell surface ligands and EphA receptor tyrosine kinases (RTKs) with the organization of these compartments was ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID