BAIT

ROPGEF2

ATROPGEF2, KINASE PARTNER PROTEIN-LIKE, KPP-LIKE, RHO guanyl-nucleotide exchange factor 2, T1N6.8, T1N6_8, AT1G01700
Rop guanine nucleotide exchange factor 2
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

ARAC5

ARABIDOPSIS THALIANA GERANYLGERANYLATED PROTEIN 3, ATGP3, ATROP4, RAC-LIKE GTP BINDING PROTEIN, RAC-like GTP binding protein 5, RHO-LIKE GTP BINDING PROTEIN 4, ROP4, AT1G75840
Rac-like GTP-binding protein ARAC5
GO Process (0)
GO Function (4)
GO Component (5)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A new family of RhoGEFs activates the Rop molecular switch in plants.

Berken A, Thomas C, Wittinghofer A

In plants, the small GTP-binding proteins called Rops work as signalling switches that control growth, development and plant responses to various environmental stimuli. Rop proteins (Rho of plants, Rac-like and AtRac in Arabidopsis thaliana) belong to the Rho family of Ras-related GTP-binding proteins that turn on signalling pathways by switching from a GDP-bound inactive to a GTP-bound active conformation. Activation ... [more]

Nature Aug. 25, 2005; 436(7054);1176-80 [Pubmed: 15980860]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ROPGEF2 ARAC5
Biochemical Activity
Biochemical Activity

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Low-BioGRID
331281

Curated By

  • BioGRID