EIN2
Gene Ontology Biological Process
- auxin polar transport [IMP]
- cell death [NAS]
- cell division [IMP]
- cellular response to iron ion [IEP]
- defense response by callose deposition in cell wall [IMP]
- defense response to bacterium [IMP]
- defense response to fungus [IMP]
- establishment of planar polarity [IGI]
- ethylene-activated signaling pathway [TAS]
- jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway [TAS]
- leaf senescence [IMP]
- negative regulation of defense response [IMP]
- positive regulation of abscisic acid-activated signaling pathway [IMP]
- regulation of stomatal movement [IMP]
- response to ethylene [IMP]
- response to heat [IMP]
- response to hormone [IMP]
- response to jasmonic acid [IMP]
- response to molecule of bacterial origin [IMP]
- response to osmotic stress [IMP]
- response to oxidative stress [TAS]
- response to salt stress [IMP]
- root hair cell differentiation [IGI]
- sugar mediated signaling pathway [TAS]
- vasculature development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ETR1
Gene Ontology Biological Process
- cell division [IMP]
- cellular response to iron ion [IEP]
- cytokinin metabolic process [IMP]
- defense response [TAS]
- defense response by callose deposition in cell wall [IMP]
- defense response to bacterium [IMP]
- detection of ethylene stimulus [IMP]
- hydrogen peroxide biosynthetic process [IMP]
- jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway [TAS]
- negative regulation of ethylene-activated signaling pathway [TAS]
- regulation of seedling development [IMP]
- regulation of stomatal movement [IMP]
- response to abscisic acid [IMP]
- response to auxin [IMP]
- response to ethylene [IMP]
- response to gibberellin [IMP]
- response to heat [IMP]
- response to insect [IMP]
- response to molecule of bacterial origin [IMP]
- response to salt stress [IEP]
- sugar mediated signaling pathway [TAS]
- vasculature development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1.
Genetic studies have identified the membrane protein EIN2 (ethylene insensitive 2) as a central component of ethylene signalling in Arabidopsis. In addition, EIN2 might take part in multiple hormone signalling pathways and in response to pathogens as demonstrated by recent genetic and biochemical studies. Here we show, by an integrated approach using in vivo and in vitro fluorescence techniques, that ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| EIN2 ETR1 | FRET FRET An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins. | Low | - | BioGRID | - | |
| EIN2 ETR1 | Reconstituted Complex Reconstituted Complex An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator. | Low | - | BioGRID | - | |
| EIN2 ETR1 | Reconstituted Complex Reconstituted Complex An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator. | Low | - | BioGRID | - |
Curated By
- BioGRID