BAIT

APX5

T19K4.100, ascorbate peroxidase 5, AT4G35970
L-ascorbate peroxidase
GO Process (0)
GO Function (2)
GO Component (0)

Gene Ontology Molecular Function

Arabidopsis thaliana (Columbia)
PREY

AKR2

AFT, AKR2A, F15J1.20, F15J1_20, ankyrin repeat-containing protein 2, AT4G35450
ankyrin repeat domain-containing protein 2
Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

ANKYRIN REPEAT-CONTAINING PROTEIN 2A is an essential molecular chaperone for peroxisomal membrane-bound ASCORBATE PEROXIDASE3 in Arabidopsis.

Shen G, Kuppu S, Venkataramani S, Wang J, Yan J, Qiu X, Zhang H

Arabidopsis thaliana ANKYRIN REPEAT-CONTAINING PROTEIN 2A (AKR2A) interacts with peroxisomal membrane-bound ASCORBATE PEROXIDASE3 (APX3). This interaction involves the C-terminal sequence of APX3 (i.e., a transmembrane domain plus a few basic amino acid residues). The specificity of the AKR2A-APX3 interaction suggests that AKR2A may function as a molecular chaperone for APX3 because binding of AKR2A to the transmembrane domain can prevent ... [more]

Plant Cell Mar. 01, 2010; 22(3);811-31 [Pubmed: 20215589]

Throughput

  • Low Throughput

Curated By

  • BioGRID